SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance

Cancer cells acquire unlimited proliferative capacity by either re-expressing telomerase or inducing alternative lengthening of telomeres (ALT), which relies on telomere recombination. Here, we show that ALT recombination requires coordinate regulation of the SMX and BTR complexes to ensure the appr...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Cell
Päätekijät: Panier, Stephanie, Maric, Marija, Hewitt, Graeme, Mason-Osann, Emily, Gali, Himabindu, Dai, Anqi, Labadorf, Adam, Guervilly, Jean-Hugues, Ruis, Philip, Segura-Bayona, Sandra, Belan, Ondrej, Marzec, Paulina, Gaillard, Pierre-Henri L., Flynn, Rachel L., Boulton, Simon J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863466/
https://ncbi.nlm.nih.gov/pubmed/31447390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.010
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