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SLX4 gains weight with SUMO in genome maintenance

Replication stress has emerged as a key driver of oncogenesis but also represents an Achilles' heel of cancer cells. Newly reported SUMO binding and SUMO ligase functions of the DNA repair protein SLX4 that influence the outcome of replication stress open new avenues for investigating the roles...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Oncol
Hauptverfasser: Guervilly, Jean-Hugues, Gaillard, Pierre-Henri L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905331/
https://ncbi.nlm.nih.gov/pubmed/27308578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1008297
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