SLX4 gains weight with SUMO in genome maintenance

Replication stress has emerged as a key driver of oncogenesis but also represents an Achilles' heel of cancer cells. Newly reported SUMO binding and SUMO ligase functions of the DNA repair protein SLX4 that influence the outcome of replication stress open new avenues for investigating the roles...

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Udgivet i:Mol Cell Oncol
Main Authors: Guervilly, Jean-Hugues, Gaillard, Pierre-Henri L
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905331/
https://ncbi.nlm.nih.gov/pubmed/27308578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1008297
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