Non-covalent Interactions with SUMO and Ubiquitin Orchestrate Distinct Functions of the SLX4 Complex in Genome Maintenance

SLX4, a coordinator of multiple DNA structure-specific endonucleases, is important for several DNA repair pathways. Non-covalent interactions of SLX4 with ubiquitin are required for localizing SLX4 to DNA-interstrand crosslinks (ICLs), yet how SLX4 is targeted to other functional contexts remains un...

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Bibliografske podrobnosti
izdano v:Mol Cell
Main Authors: Ouyang, Jian, Garner, Elizabeth, Hallet, Alexander, Nguyen, Hai Dang, Rickman, Kimberly A., Gill, Grace, Smogorzewska, Agata, Zou, Lee
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289429/
https://ncbi.nlm.nih.gov/pubmed/25533185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.11.015
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