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Wss1 Is a SUMO-Dependent Isopeptidase That Interacts Genetically with the Slx5-Slx8 SUMO-Targeted Ubiquitin Ligase

Protein sumoylation plays an important but poorly understood role in controlling genome integrity. In Saccharomyces cerevisiae, the Slx5-Slx8 SUMO-targeted Ub ligase appears to be needed to ubiquitinate sumoylated proteins that arise in the absence of the Sgs1 DNA helicase. WSS1, a high-copy-number...

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Detalhes bibliográficos
Main Authors: Mullen, Janet R., Chen, Chi-Fu, Brill, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916399/
https://ncbi.nlm.nih.gov/pubmed/20516210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01649-09
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