Stabilization and formulation of a recombinant Human Cytomegalovirus vector for use as a candidate HIV-1 vaccine

Live attenuated viral vaccine/vector candidates are inherently unstable and infectivity titer losses can readily occur without defining appropriate formulations, storage conditions and clinical handling practices. During initial process development of a candidate vaccine against HIV-1 using a recomb...

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Pubblicato in:Vaccine
Autori principali: Kumru, Ozan S., Saleh-Birdjandi, Soraia, Antunez, Lorena R., Sayeed, Eddy, Robinson, David, van den Worm, Sjoerd, Diemer, Geoffrey S., Perez, Wilma, Caposio, Patrizia, Früh, Klaus, Joshi, Sangeeta B., Volkin, David B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Science 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863464/
https://ncbi.nlm.nih.gov/pubmed/31548012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.09.027
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