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DNA Polymerase Delta Synthesizes Both Strands during Break-Induced Replication

Break-induced replication (BIR) is a pathway of homology-directed repair that repairs one-ended DNA breaks, such as those formed at broken replication forks or uncapped telomeres. In contrast to conventional S phase DNA synthesis, BIR proceeds by a migrating D-loop and results in conservative synthe...

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Dettagli Bibliografici
Pubblicato in:Mol Cell
Autori principali: Donnianni, Roberto A., Zhou, Zhi-Xiong, Lujan, Scott A., Al-Zain, Amr, Garcia, Valerie, Glancy, Eleanor, Burkholder, Adam B., Kunkel, Thomas A., Symington, Lorraine S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862718/
https://ncbi.nlm.nih.gov/pubmed/31495565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.033
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