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Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication

Most current evidence indicates that DNA polymerases ε and δ, respectively, perform the bulk of leading and lagging strand replication of the eukaryotic nuclear genome. Given that ribonucleotide and mismatch incorporation rates by these replicases influence somatic and germline patterns of variation...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Zhou, Zhi-Xiong, Lujan, Scott A., Burkholder, Adam B., Garbacz, Marta A., Kunkel, Thomas A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728351/
https://ncbi.nlm.nih.gov/pubmed/31488849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11995-z
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