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A major role of DNA polymerase δ in replication of both the leading and lagging DNA strands
Genetic studies with S. cerevisiae Polδ (pol3-L612M) and Polε (pol2-M644G) mutant alleles, each of which display a higher rate for the generation of a specific mismatch, have led to the conclusion that Polε is the primary leading strand replicase and that Polδ is restricted to replicating the laggin...
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| Pubblicato in: | Mol Cell |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4517859/ https://ncbi.nlm.nih.gov/pubmed/26145172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.05.038 |
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