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PCNA binding domains in all three subunits of yeast DNA polymerase δ modulate its function in DNA replication

DNA polymerase δ (Polδ) plays an essential role in replication from yeast to humans. Polδ in Saccharomyces cerevisiae is comprised of three subunits, the catalytic subunit Pol3 and the accessory subunits Pol31 and Pol32. Yeast Polδ exhibits a very high processivity in synthesizing DNA with the proli...

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Detalhes bibliográficos
Main Authors: Acharya, Narottam, Klassen, Roland, Johnson, Robert E., Prakash, Louise, Prakash, Satya
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207673/
https://ncbi.nlm.nih.gov/pubmed/22003126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109981108
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