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Identification of two functional PCNA binding domains in human DNA polymerase κ
Previously, we have shown that human DNA polymerase (Pol) η has two functional PCNA binding motifs, PIP1 and PIP2, and that a C-terminal deletion of Polη that lacks the ubiquitin-binding UBZ domain and the PIP2 domain but retains the PIP1 domain promotes normal levels of translesion synthesis (TLS)...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074225/ https://ncbi.nlm.nih.gov/pubmed/24848457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gtc.12156 |
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