A Single Domain in Human DNA Polymerase ι Mediates Interaction with PCNA: Implications for Translesion DNA Synthesis

DNA polymerases (Pols) of the Y family rescue stalled replication forks by promoting replication through DNA lesions. Humans have four Y family Pols, η, ι, κ, and Rev1, of which Pols η, ι, and κ have been shown to physically interact with proliferating cell nuclear antigen (PCNA) and be functionally...

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Detalhes bibliográficos
Main Authors: Haracska, Lajos, Acharya, Narottam, Unk, Ildiko, Johnson, Robert E., Hurwitz, Jerard, Prakash, Louise, Prakash, Satya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Chromosome Structure and Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544020/
https://ncbi.nlm.nih.gov/pubmed/15657443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.3.1183-1190.2005
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