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End Resection at Double-Strand Breaks: Mechanism and Regulation
RecA/Rad51 catalyzed pairing of homologous DNA strands, initiated by polymerization of the recombinase on single-stranded DNA (ssDNA), is a universal feature of homologous recombination (HR). Generation of ssDNA from a double-strand break (DSB) requires nucleolytic degradation of the 5′-terminated s...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107989/ https://ncbi.nlm.nih.gov/pubmed/25085909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a016436 |
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