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Mechanism and Regulation of DNA End Resection in Eukaryotes
The repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) is initiated by nucleolytic degradation of the 5′ terminated strands in a process termed end resection. End resection generates 3′ single-stranded DNA tails, substrates for Rad51 to catalyze homologous pairing and exchang...
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| Veröffentlicht in: | Crit Rev Biochem Mol Biol |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4957645/ https://ncbi.nlm.nih.gov/pubmed/27098756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2016.1172552 |
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