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RPA coordinates DNA end resection and prevents formation of DNA hairpins
Replication Protein A (RPA) is an essential eukaryotic single-stranded DNA binding protein with a central role in DNA metabolism. RPA directly participates in DNA double-strand break repair by stimulating 5’-3’ end resection by the Sgs1/BLM helicase and Dna2 endonuclease in vitro. Here we investigat...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855855/ https://ncbi.nlm.nih.gov/pubmed/23706822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.04.032 |
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