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DNA end resection: many nucleases make light work
Double strand breaks (DSBs) are deleterious DNA lesions and if left unrepaired result in severe genomic instability. Cells use two main pathways to repair DSBs: homologous recombination (HR) or non-homologous end joining (NHEJ) depending on the phase of the cell cycle and the nature of the DSB ends....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760233/ https://ncbi.nlm.nih.gov/pubmed/19473888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.04.017 |
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