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Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
DNA ends exposed after introduction of double-strand breaks (DSBs) undergo 5′-3′ nucleolytic degradation to generate single-stranded DNA (ssDNA), the substrate for binding by the Rad51 protein to initiate homologous recombination. This process is poorly understood in eukaryotes, but several factors...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3818707/ https://ncbi.nlm.nih.gov/pubmed/18806779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07312 |
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