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Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double strand break ends
Formation of single-strand DNA (ssDNA) tails at a double-strand break (DSB) is a key step in homologous recombination and DNA damage signaling. The enzyme(s) producing ssDNA at DSBs in eukaryotes remains unknown. We monitored 5’-strand resection at inducible DSB ends and identified proteins required...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662516/ https://ncbi.nlm.nih.gov/pubmed/18805091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.08.037 |
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