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Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation
DNA recombination pathways are cell cycle regulated to coordinate with replication. Cyclin-dependent kinase (Cdk1) promotes efficient 5'-strand resection at DNA double strand breaks (DSBs), the initial step of homologous recombination and damage checkpoint activation. The Mre11–Rad50–Xrs2 compl...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3168961/ https://ncbi.nlm.nih.gov/pubmed/21841787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2105 |
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