Rad52 Restrains Resection at DNA Double-Strand Break Ends in Yeast

Rad52 is a key factor for homologous recombination (HR) in yeast. Rad52 helps assemble Rad51-ssDNA nucleoprotein filaments that catalyze DNA strand exchange, and it mediates single-strand DNA annealing. We find that Rad52 has an even earlier function in HR in restricting DNA double-stranded break en...

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Gepubliceerd in:Mol Cell
Hoofdauteurs: Yan, Zhenxin, Xue, Chaoyou, Kumar, Sandeep, Crickard, J. Brooks, Yu, Yang, Wang, Weibin, Pham, Nhung, Li, Yuxi, Niu, Hengyao, Sung, Patrick, Greene, Eric C., Ira, Grzegorz
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898758/
https://ncbi.nlm.nih.gov/pubmed/31542296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.08.017
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