A novel role of the Dna2 translocase function in DNA break resection

DNA double-strand break repair by homologous recombination entails nucleolytic resection of the 5′ strand at break ends. Dna2, a flap endonuclease with 5′–3′ helicase activity, is involved in the resection process. The Dna2 helicase activity has been implicated in Okazaki fragment processing during...

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Vydáno v:Genes Dev
Hlavní autoři: Miller, Adam S., Daley, James M., Pham, Nhung Tuyet, Niu, Hengyao, Xue, Xiaoyu, Ira, Grzegorz, Sung, Patrick
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2017
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393064/
https://ncbi.nlm.nih.gov/pubmed/28336516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.295659.116
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