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Biochemical Mechanism of DSB End Resection and its Regulation

DNA double-strand breaks (DSBs) in cells can undergo nucleolytic degradation to generate long 3′ single-stranded DNA tails. This process is termed DNA end resection, and its occurrence effectively commits to break repair via homologous recombination, which entails the acquisition of genetic informat...

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Bibliografiske detaljer
Udgivet i:DNA Repair (Amst)
Main Authors: Daley, James M., Niu, Hengyao, Miller, Adam S., Sung, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522330/
https://ncbi.nlm.nih.gov/pubmed/25956866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.04.015
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