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Interplay between Ku and Replication Protein A in the Restriction of Exo1-mediated DNA Break End Resection

DNA double-strand breaks can be eliminated via non-homologous end joining or homologous recombination. Non-homologous end joining is initiated by the association of Ku with DNA ends. In contrast, homologous recombination entails nucleolytic resection of the 5′-strands, forming 3′-ssDNA tails that be...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Krasner, Danielle S., Daley, James M., Sung, Patrick, Niu, Hengyao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513135/
https://ncbi.nlm.nih.gov/pubmed/26067273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.660191
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