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DNA double-strand break processing: the beginning of the end

Nucleolytic processing of DNA double-strand breaks (DSBs) generates 3′ ssDNA tails that are essential for the assembly of DNA damage checkpoint signaling and DNA repair protein complexes. Genetic studies have provided evidence that multiple nuclease activities are involved in DSB end resection. Thre...

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Detalhes bibliográficos
Main Authors: Raynard, Steven, Niu, Hengyao, Sung, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751443/
https://ncbi.nlm.nih.gov/pubmed/18981468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1742408
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