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Mechanisms restraining break‐induced replication at two‐ended DNA double‐strand breaks
DNA synthesis during homologous recombination is highly mutagenic and prone to template switches. Two‐ended DNA double‐strand breaks (DSBs) are usually repaired by gene conversion with a short patch of DNA synthesis, thus limiting the mutation load to the vicinity of the DSB. Single‐ended DSBs are r...
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| Foilsithe in: | EMBO J |
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| Main Authors: | , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
John Wiley and Sons Inc.
2021
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8126933/ https://ncbi.nlm.nih.gov/pubmed/33844333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104847 |
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