Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication.

In wild-type diploid cells of Saccharomyces cerevisiae, an HO endonuclease-induced double-strand break (DSB) at the MAT locus can be efficiently repaired by gene conversion using the homologous chromosome sequences. Repair of the broken chromosome was nearly eliminated in rad52delta diploids; 99% lo...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Malkova, A, Ivanov, E L, Haber, J E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38948/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692957/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7131
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