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DNA end resection - unraveling the tail
Homology-dependent repair of DNA double-strand breaks (DSB) initiates by the 5′-3′ resection of the DNA ends to create single-stranded DNA (ssDNA), the substrate for Rad51/RecA binding. Long tracts of ssDNA are also required for activation of the ATR-mediated checkpoint response. Thus, identifying t...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046306/ https://ncbi.nlm.nih.gov/pubmed/21227759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.12.004 |
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