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DNA end resection - unraveling the tail

Homology-dependent repair of DNA double-strand breaks (DSB) initiates by the 5′-3′ resection of the DNA ends to create single-stranded DNA (ssDNA), the substrate for Rad51/RecA binding. Long tracts of ssDNA are also required for activation of the ATR-mediated checkpoint response. Thus, identifying t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mimitou, Eleni P., Symington, Lorraine S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046306/
https://ncbi.nlm.nih.gov/pubmed/21227759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.12.004
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