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Mechanisms and regulation of DNA end resection
DNA double-strand breaks (DSBs) are highly hazardous for genome integrity, because failure to repair these lesions can lead to genomic instability. DSBs can arise accidentally at unpredictable locations into the genome, but they are also normal intermediates in meiotic recombination. Moreover, the n...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944052/ https://ncbi.nlm.nih.gov/pubmed/20647996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.165 |
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