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The MRX Complex Plays Multiple Functions in Resection of Yku- and Rif2-Protected DNA Ends
The ends of both double-strand breaks (DSBs) and telomeres undergo tightly regulated 5′ to 3′ resection. Resection of DNA ends, which is specifically inhibited during the G1 cell cycle phase, requires the MRX complex, Sae2, Sgs1 and Exo1. Moreover, it is negatively regulated by the non-homologous en...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2994746/ https://ncbi.nlm.nih.gov/pubmed/21152442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014142 |
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