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The MRX Complex Plays Multiple Functions in Resection of Yku- and Rif2-Protected DNA Ends

The ends of both double-strand breaks (DSBs) and telomeres undergo tightly regulated 5′ to 3′ resection. Resection of DNA ends, which is specifically inhibited during the G1 cell cycle phase, requires the MRX complex, Sae2, Sgs1 and Exo1. Moreover, it is negatively regulated by the non-homologous en...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bonetti, Diego, Clerici, Michela, Manfrini, Nicola, Lucchini, Giovanna, Longhese, Maria Pia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994746/
https://ncbi.nlm.nih.gov/pubmed/21152442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014142
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