Mechanisms and regulation of DNA end resection

DNA double-strand breaks (DSBs) are highly hazardous for genome integrity, because failure to repair these lesions can lead to genomic instability. DSBs can arise accidentally at unpredictable locations into the genome, but they are also normal intermediates in meiotic recombination. Moreover, the n...

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Bibliografske podrobnosti
Main Authors: Longhese, Maria Pia, Bonetti, Diego, Manfrini, Nicola, Clerici, Michela
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
EMBO Member's Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944052/
https://ncbi.nlm.nih.gov/pubmed/20647996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.165
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