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The Mre11 Nuclease Is Not Required for 5′ to 3′ Resection at Multiple HO-Induced Double-Strand Breaks

Current hypotheses suggest the Mre11 nuclease activity could be directly involved in double-strand break (DSB) resection in the presence of a large number of DSBs or limited to processing abnormal DNA ends. To distinguish between these possibilities, we used two methods to create large numbers of DS...

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Detalhes bibliográficos
Main Authors: Llorente, Bertrand, Symington, Lorraine S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522228/
https://ncbi.nlm.nih.gov/pubmed/15485933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.21.9682-9694.2004
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