The Mre11 Nuclease Is Not Required for 5′ to 3′ Resection at Multiple HO-Induced Double-Strand Breaks

Current hypotheses suggest the Mre11 nuclease activity could be directly involved in double-strand break (DSB) resection in the presence of a large number of DSBs or limited to processing abnormal DNA ends. To distinguish between these possibilities, we used two methods to create large numbers of DS...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Llorente, Bertrand, Symington, Lorraine S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2004
Soggetti:
DNA Dynamics and Chromosome Structure
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC522228/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15485933/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.21.9682-9694.2004
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