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Break-induced replication occurs by conservative DNA synthesis
Break-induced replication (BIR) refers to recombination-dependent DNA synthesis initiated from one end of a DNA double-strand break and can extend for more than 100 kb. BIR initiates by Rad51-catalyzed strand invasion, but the mechanism for DNA synthesis is not known. Here, we used BrdU incorporatio...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746906/ https://ncbi.nlm.nih.gov/pubmed/23898170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309800110 |
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