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Break-induced replication occurs by conservative DNA synthesis

Break-induced replication (BIR) refers to recombination-dependent DNA synthesis initiated from one end of a DNA double-strand break and can extend for more than 100 kb. BIR initiates by Rad51-catalyzed strand invasion, but the mechanism for DNA synthesis is not known. Here, we used BrdU incorporatio...

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Hlavní autoři: Donnianni, Roberto A., Symington, Lorraine S.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746906/
https://ncbi.nlm.nih.gov/pubmed/23898170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309800110
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