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RPA stabilization of single-stranded DNA is critical for break-induced replication
DNA double strand breaks (DSBs) are cytotoxic lesions that must be accurately repaired to maintain genome stability. Replication protein A (RPA) plays an important role in homology-dependent repair of DSBs by protecting the single-stranded DNA (ssDNA) intermediates formed by end resection and facili...
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| Veröffentlicht in: | Cell Rep |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5218512/ https://ncbi.nlm.nih.gov/pubmed/28009302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.003 |
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