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Aberrant Double-Strand Break Repair Resulting in Half Crossovers in Mutants Defective for Rad51 or the DNA Polymerase δ Complex

Homologous recombination is an error-free mechanism for the repair of DNA double-strand breaks (DSBs). Most DSB repair events occur by gene conversion limiting loss of heterozygosity (LOH) for markers downstream of the site of repair and restricting deleterious chromosome rearrangements. DSBs with o...

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Podrobná bibliografie
Hlavní autoři: Smith, Catherine E., Lam, Alicia F., Symington, Lorraine S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648250/
https://ncbi.nlm.nih.gov/pubmed/19139272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01469-08
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