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Aberrant Double-Strand Break Repair Resulting in Half Crossovers in Mutants Defective for Rad51 or the DNA Polymerase δ Complex

Homologous recombination is an error-free mechanism for the repair of DNA double-strand breaks (DSBs). Most DSB repair events occur by gene conversion limiting loss of heterozygosity (LOH) for markers downstream of the site of repair and restricting deleterious chromosome rearrangements. DSBs with o...

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Detalhes bibliográficos
Main Authors: Smith, Catherine E., Lam, Alicia F., Symington, Lorraine S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648250/
https://ncbi.nlm.nih.gov/pubmed/19139272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01469-08
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