Synthesis and μ-Opioid Activity of the Primary Metabolites of Carfentanil

[Image: see text] Carfentanil is a synthetic opioid significantly more potent than clinically prescribed fentanyl. The primary metabolites of carfentanil, generated from human liver microsomes, were structurally confirmed through chemical synthesis. The synthesized compounds were evaluated for μ-opi...

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Detaylı Bibliyografya
Yayımlandı:ACS Med Chem Lett
Asıl Yazarlar: Hsu, Fu-Lian, Walz, Andrew J., Myslinski, James M., Kong, Li, Feasel, Michael G., Goralski, Tyler D. P., Rose, Tim, Cooper, Nicholas J., Roughley, Neil, Timperley, Christopher M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2019
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862335/
https://ncbi.nlm.nih.gov/pubmed/31749912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00404
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