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‘Carba’-carfentanil (trans isomer): a μ opioid receptor (MOR) partial agonist with a distinct binding mode

There is strong evidence to indicate that a positively charged nitrogen of endogenous and exogenous opioid ligands forms a salt bridge with the Asp residue in the third transmembrane helix of opioid receptors. To further examine the role of this electrostatic interaction in opioid receptor binding a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Weltrowska, Grazyna, Lemieux, Carole, Chung, Nga N., Guo, Jason J., Wilkes, Brian C., Schiller, Peter W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149825/
https://ncbi.nlm.nih.gov/pubmed/25129170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.07.033
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