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‘Carba’-Analogues of Fentanyl are Opioid Receptor Agonists
There is evidence to indicate that the Asp residue in the third transmembrane helix (TMH) of opioid receptors forms a salt bridge with the positively charged nitrogen of endogenous and exogenous opioid ligands. To further examine the role of this electrostatic interaction in receptor binding and act...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848705/ https://ncbi.nlm.nih.gov/pubmed/20218625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9019068 |
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