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Synthesis and μ-Opioid Activity of the Primary Metabolites of Carfentanil

[Image: see text] Carfentanil is a synthetic opioid significantly more potent than clinically prescribed fentanyl. The primary metabolites of carfentanil, generated from human liver microsomes, were structurally confirmed through chemical synthesis. The synthesized compounds were evaluated for μ-opi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:ACS Med Chem Lett
Κύριοι συγγραφείς: Hsu, Fu-Lian, Walz, Andrew J., Myslinski, James M., Kong, Li, Feasel, Michael G., Goralski, Tyler D. P., Rose, Tim, Cooper, Nicholas J., Roughley, Neil, Timperley, Christopher M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Chemical Society 2019
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862335/
https://ncbi.nlm.nih.gov/pubmed/31749912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00404
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