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Integration of TGF-β-induced Smad signaling in the insulin-induced transcriptional response in endothelial cells
Insulin signaling governs many processes including glucose homeostasis and metabolism, and is therapeutically used to treat hyperglycemia in diabetes. We demonstrated that insulin-induced Akt activation enhances the sensitivity to TGF-β by directing an increase in cell surface TGF-β receptors from a...
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| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6861289/ https://ncbi.nlm.nih.gov/pubmed/31740700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53490-x |
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