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Enhanced TGF-β Signaling Contributes to the Insulin-Induced Angiogenic Responses of Endothelial Cells

Angiogenesis, the development of new blood vessels, is a key process in disease. We reported that insulin promotes translocation of transforming growth factor β (TGF-β) receptors to the plasma membrane of epithelial and fibroblast cells, thus enhancing TGF-β responsiveness. Since insulin promotes an...

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Détails bibliographiques
Publié dans:iScience
Auteurs principaux: Budi, Erine H., Mamai, Ons, Hoffman, Steven, Akhurst, Rosemary J., Derynck, Rik
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348203/
https://ncbi.nlm.nih.gov/pubmed/30684493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.12.038
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