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Repurposing endogenous immune pathways to tailor and control chimeric antigen receptor T cell functionality
Endowing chimeric antigen receptor (CAR) T cells with additional potent functionalities holds strong potential for improving their antitumor activity. However, because potency could be deleterious without control, these additional features need to be tightly regulated. Immune pathways offer a wide a...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6853973/ https://ncbi.nlm.nih.gov/pubmed/31723132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13088-3 |
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