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A Versatile Safeguard for Chimeric Antigen Receptor T-Cell Immunotherapies
CAR T-cell therapies hold great promise for treating a range of malignancies but are however challenged by the complexity of their production and by the adverse events related to their activity. Here we report the development of the CubiCAR, a tri-functional CAR architecture that enables CAR T-cell...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5997667/ https://ncbi.nlm.nih.gov/pubmed/29895885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27264-w |
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