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Optimized tuning of TALEN specificity using non-conventional RVDs
A key feature when designing DNA targeting tools and especially nucleases is specificity. The ability to control and tune this important parameter represents an invaluable advance to the development of such molecular scissors. Here, we identified and characterized new non-conventional RVDs (ncRVDs)...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4311247/ https://ncbi.nlm.nih.gov/pubmed/25632877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08150 |
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