Repurposing endogenous immune pathways to tailor and control chimeric antigen receptor T cell functionality

Endowing chimeric antigen receptor (CAR) T cells with additional potent functionalities holds strong potential for improving their antitumor activity. However, because potency could be deleterious without control, these additional features need to be tightly regulated. Immune pathways offer a wide a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sachdeva, Mohit, Busser, Brian W., Temburni, Sonal, Jahangiri, Billal, Gautron, Anne-Sophie, Maréchal, Alan, Juillerat, Alexandre, Williams, Alan, Depil, Stéphane, Duchateau, Philippe, Poirot, Laurent, Valton, Julien
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853973/
https://ncbi.nlm.nih.gov/pubmed/31723132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13088-3
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados