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Guiding tail-anchored membrane proteins to the endoplasmic reticulum in a chaperone cascade

Newly synthesized integral membrane proteins must traverse the aqueous cytosolic environment before arrival at their membrane destination and are prone to aggregation, misfolding, and mislocalization during this process. The biogenesis of integral membrane proteins therefore poses acute challenges t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awdur: Shan, Shu-ou
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851334/
https://ncbi.nlm.nih.gov/pubmed/31575659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.006197
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