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Endoplasmic Reticulum Targeting and Insertion of Tail-Anchored Membrane Proteins by the GET Pathway

Hundreds of eukaryotic membrane proteins are anchored to membranes by a single transmembrane domain at their carboxyl terminus. Many of these tail-anchored (TA) proteins are posttranslationally targeted to the endoplasmic reticulum (ER) membrane for insertion by the guided-entry of TA protein insert...

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Bibliographic Details
Main Authors: Denic, Vladimir, Dötsch, Volker, Sinning, Irmgard
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721280/
https://ncbi.nlm.nih.gov/pubmed/23906715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a013334
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