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The GET Complex Mediates Insertion of Tail-Anchored Proteins into the ER Membrane
Tail-anchored (TA) proteins, defined by the presence of a single C-terminal transmembrane domain (TMD), play critical roles throughout the secretory pathway and in mitochondria, yet the machinery responsible for their proper membrane insertion remains poorly characterized. Here we show that Get3, th...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cell Press
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572727/ https://ncbi.nlm.nih.gov/pubmed/18724936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.06.025 |
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