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The GET Complex Mediates Insertion of Tail-Anchored Proteins into the ER Membrane

Tail-anchored (TA) proteins, defined by the presence of a single C-terminal transmembrane domain (TMD), play critical roles throughout the secretory pathway and in mitochondria, yet the machinery responsible for their proper membrane insertion remains poorly characterized. Here we show that Get3, th...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Schuldiner, Maya, Metz, Jutta, Schmid, Volker, Denic, Vladimir, Rakwalska, Magdalena, Schmitt, Hans Dieter, Schwappach, Blanche, Weissman, Jonathan S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572727/
https://ncbi.nlm.nih.gov/pubmed/18724936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.06.025
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