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The Mechanism of Tail Anchored Protein Insertion into the ER Membrane

Tail-anchored (TA) proteins access the secretory pathway via posttranslational insertion of their C-terminal transmembrane domain into the endoplasmic reticulum (ER). Get3 is an ATPase that delivers TA proteins to the ER by interacting with the Get1-Get2 transmembrane complex but how Get3’s nucleoti...

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書目詳細資料
Main Authors: Wang, Fei, Whynot, Andrew, Tung, Matthew, Denic, Vladimir
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614002/
https://ncbi.nlm.nih.gov/pubmed/21835666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.07.020
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